Desy Sofyah Hartina

Fakultas Kedokteran Gigi Universitas Jember, Indonesia

Yani Corvianindya Rahayu, Atik Kurniawati

Bagian Biologi Oral, Fakultas Kedokteran Gigi Universitas Jember, Indonesia

DOI: https://doi.org/10.19184/stoma.v20i2.44006

ABSTRACT 

Candidiasis is an opportunistic fungal infection caused by Candida albicans. The prevalence of candidiasis in Indonesia is around 20-25%, it can attack the skin, nails, hair, throat, and mouth. One of the fungal infections that occur in the oral cavity is oral candidiasis. Oral candidiasis is caused by overgrowth of Candida albicans species in the oral cavity which is dominated by Candida albicans  as  much  as  85-95%.  One  of  the  treatments  using  herbal  medicinal  plants  is  cocoa  peel  containing  active  compounds including phenolics, flavonoids, tannins, and terpenoids which are thought to be antifungal. The aim was to determine the inhibition of cocoa peel extract on the growth of Candida albicans. This study used the disc diffusion method with 4 samples in eachstudy group. The  research  group  consisted  of  5 treatment  groups  (10%, 20%,  40%,  80%,  and  100%  cocoa  peel  extract), positive  controlgroup  (nystatin),  and  negative  control  group  (sterile  aquades).  Data  were  analyzed  using  One  Way  Anova  test  and  LSD  (Least Significant Difference) test. Concentrations of extracts of cocoa pods 100% and 80% have the ability to inhibit the growth ofCandida albicans.