Pengaruh Patch Ekstrak Buah Delima Merah Terhadap Percepatan Penyembuhan Traumatik Ulser pada Tikus Wistar
(TheEffect of Red Pomegranate Extract in Patch on the Accelerated Healing of Traumatic Ulcer in Wistar Rats)
Embedded Files
Gardenisti Putri Maheswari
Fakultas Kedokteran Gigi, Universitas Jember, Indonesia
Sri Hernawati
Bagian Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Jember, Indonesia
Endah Lestari
Bagian Biomedik, Fakultas Kedokteran Gigi, Universitas Jember, Indonesia
DOI: https://doi.org/10.19184/stoma.v21i1.47337
ABSTRACT
Traumatic ulcer is one of the disorders of the oral cavity that can be caused by mechanical, thermal, and chemical. Patch one of traumatic ulcer treatment choice are being developed, but the available patch isuneconomic and have side effects. Therefore, the use of natural ingredients is an alternative treatment, such as pomegranate. Pomegranate is known to contain bioactive elements, that can act as anti-inflammatory and antioxidant, that it can accelerate the healing of traumatic ulcers. The aim of this research isto determine the effect of the pomegranate extract patch on the acceleration of ulcer healing. Sample in this research were 25traumatic ulcered wistar rats which were divided into 5 groups. All groups were condensed the pomegranate extract patch with a concentration of 12.5%; 25%; 50%, positive control (taisho patch), and negative control (placebo). The red pomegranate extract patch can accelerate the healing of traumatic ulcers. There was a significant difference in healing time between all groups (p<0.05), except between the positive control group with a concentration of 50%.pomegranate extract patch affected the acceleration of ulcer healing, with a concentration of 50% pomegranate extract patch was the fastest.
Published
30-03-2024
Issue
Vol. 21 No. 1 2024: Jurnal Stomatognatic
Pages
61-64
License
Copyright (c) 2024 Jurnal Stomatognatic
Page updated
Report abuse